Damnit I was just about to post:
INB4 - DC's whine about the new plays, GLB sucks, and all the games will be high scoring................
but you beat me to it

Doesn't matter. We all play with the same tools. And the goal is not to beat GLB but beat the other team however that needs to be. The best defense will still be the ones that adjust the quickest and does the best job slowing these plays down.
But with the massive amounts of plays it will become more of a chess match. Scouting and flexibility become very important. IT becomes a if you set up to stop this play then this play will be open. So it will be up to the DC's to guess which plays the OC will run. And up to the OC's to guess which plays the DC will try to stop. And when you guess wrong bad things will happen.....