Hopefully strength and agility are both well over 80 natural by this point. If not, then you really need to get both to at least the 81 cap ASAP and may need to consider spending up to the 83 cap.
If both are already in the 80's then tackling needs to be at least 1st capped and most prefer 2nd capped although I'm not convinced it is necessary. Speed then needs to get to 68 cap.
If that is done then you can take speed higher (I prefer at least to the 77 cap) or go ahead and cap vision, stamina, and confidence.
Just for comparison my 42 currently has
91.84 natural strength
85.84 natural agility
68.48 natural speed
55.84 tackling (I'm done, I only first capped and trained up to 51)
I'm multi-training vision, confidence, stamina while taking speed up to the 81 cap. Although I can only multi-train this season and next then I have to relaxed train rest of career so I have 4 pieces of AEQ for his last 2 to 3 seasons.